Hematopoietic microenvironment

Several mechanisms may account for this phenomenon , including biochemical mechanisms , such as the overexpression of resistance-conferring proteins and physiological mechanisms involving the hematopoietic microenvironment .

这种现象由多种耐药机制导致，包括了如过度表达耐药相关蛋白的生化机制和涉及造血微环境的生理机制等。

Effects of vitamin A on hematopoietic microenvironment

维生素A对小鼠造血微环境影响的研究

Objective To study the growth characteristics of cord blood adherent cells and provide the hematopoietic microenvironment .

目的观察脐血贴壁细胞生长特性及提高体外培养脐血贴壁细胞成功率，为造血干细胞培养提供基质环境。

Some Abnormalities of Stromal Hematopoietic Microenvironment in Bone Marrow of Patients with Acute Leukemia

急性白血病患者骨髓基质造血微环境的某些异常英文

It is one of the important ways to restore hematopoietic microenvironment of promoting the functions of BMSCs .

促进BMSCs功能恢复，是修复HME的重要途径。

Hematopoietic Microenvironment of Bone Marrow of Chicken Infectious Anemia

鸡传染性贫血病骨髓造血微环境的研究

Experimental study showed that SHSBG has good bone marrow hematopoietic microenvironment protecting and improving effect in mice .

双黄升白冲剂对小鼠骨髓有良好的保护、改善造血微环境的作用。

Protection effects of injection acanthopanax senticosus on bone marrow hematopoietic microenvironment in mice with the radiation damage

刺五加对放射损伤骨髓微血管的保护作用

Aim To investigate the mechanism of the radiation burn combined injury to the bone marrow hematopoietic microenvironment in the mice .

目的探讨放烧复合伤对骨髓造血微环境损伤的机制。

The association among expression of VEGF , hematopoietic microenvironment and hematopoietic reconstitution deserve fur-ther study .

辐射后，小鼠骨髓中VEGF的改变与骨髓基质的损伤、造血恢复的关系值得进一步研究。

Objective : To investigate the injury mechanism of bone marrow hematopoietic microenvironment from PBSCT patients anterior and post pretreatment .

目的：进一步探讨外周血干细胞移植后患者骨髓造血微环境损伤的机理。

Objective To review the research progress of osteoblasts in the hematopoietic microenvironment of bone marrow and regulatory pathways and mechanisms .

目的对成骨细胞参与骨髓造血微环境的构建并在其中发挥调控作用的研究进展进行综述。

Role of osteoblasts in the hematopoietic microenvironment of bone marrow and regulatory pathways and mechanisms on securities regulatory powers

成骨细胞参与骨髓造血微环境的构建及发挥调控作用论证券监管权&中国证券监管权的依法行使及其机制性制约

However , the implementation of steady-state hematopoiesis process in vivo is dependent on the complex and complete bone marrow hematopoietic microenvironment .

然而，体内整个稳态造血过程的实现又依赖于复杂而完整的骨髓HIM。

The Study of Effects of Hematopoietic Microenvironment from Human Umbilical Cord Blood-derived Stromal Cells on the Residual Leukemia Cells and Its Mechanisms

人脐血源基质细胞新型微环境对残留白血病细胞的作用及机制探讨

Experimental study on reparative effect of human umbilical cord blood stromal cells transplantation on reconstruction of hematopoietic microenvironment and enhancement of megakaryocytopoiesis

人脐血源基质细胞移植重建造血微环境促进巨核细胞生成的实验研究

Influence of chemotherapy on hematopoietic microenvironment and effect of autologous bone marrow stromal cell infusion on the recovery of hematopoiesis after chemotherapy

化疗对造血微环境的影响及化疗后回输自体骨髓基质细胞对造血功能恢复的作用

The abnormal of stem cell , alteration of hematopoietic microenvironment and defective immunologic mechanism may play important roles in the pathogenesy of MDS .

MDS干细胞基因异常、造血微环境改变和免疫机制缺陷在发病中均起着重要作用。

Conclusion The further understanding of the relationship between osteoblasts and hematopoietic microenvironment should lead to development of new strategies directed toward clinical therapeutics of HSCs transplantation .

结论对成骨细胞与骨髓造血微环境相互作用的进一步研究，为造血干细胞的临床移植应用提供了更好的理论基础。

It can infer that Lead has strong toxicity on the hematopoietic microenvironment . and then effect the whole hematopoietic system , and may lead to the changes of peripheral blood at last .

提示铅对HIM有较强的毒性作用，进而影响了整个造血调控过程，最终可能对外周血象的改变产生重大影响。

Objective The influence of the mimic hematopoietic microenvironment and adhesion factor on the initial divisional behavior of human cord blood hematopoietic progenitors was studied in the culture system with certain cytokines .

目的在特定生长因子的培养体系中，观察模拟造血微环境及粘附因素对人类脐血造血干祖细胞早期分裂行为的影响。

Objective To determine the regulative effects of recombinant human interleukin 3 ( rhIL 3 ) and interleukin 6 ( rhIL 6 ) on bone marrow hematopoietic microenvironment .

目的了解重组人白细胞介素3（rhIL－3）和重组人白细胞介素6（rhIL－6）对骨髓造血微环境的调节作用。

Conclusion : The Stasis eliminating and Kidney tonifying Decoction can facilitate the hematopoietic microenvironment recovery , decrease the level of hematopoietic negative regulatory factors , thus facilitate the hematogenesis recovery in aplastic anemia mice .

结论：化瘀补肾汤能促进再障小鼠骨髓微环境的修复，减少造血负调控因子的释放，从而促进造血功能恢复。

There unavoidably will be many unavoidable problems in the course of transplanting , as the damage of hematopoietic microenvironment , the problem of homing of stem cells , and graft versus host reaction ( GVHR ) .

如造血微环境的破坏，干细胞归巢问题及移植后的移植物抗宿主反应（GVHR）均影响移植成败。

Result : In model group , the proliferation of bone marrow was low to the utmost , the hematopoietic microenvironment was damaged obviously , the levels of IL 2 and IFN γ in serum were higher than those in normal group .

结果：再障模型组骨髓增生极度低下，骨髓微环境明显受损，血清IL2、IFNγ水平明显增高。

Conclusion There were many abnormalities in hematopoietic inductive microenvironment ( HIM ) of acute leukemia .

结论急性白血病存在造血微环境异常。

Hematopoietic inductive microenvironment ( HIM ) is the site of implantation , proliferation , differentiation , and development for hematopoietic stem cells ( HSC ) .

骨髓间充质干细胞的增殖、分化及迁移等生物学特性受骨髓微环境的调节。

The change in cell cycle , DNA content and morphology for bone marrow stromal cells was one of impairment injury mechanisms of bone marrow hematopoietic inductive microenvironment from mice post combined radiation burn injury .

提示：放射复合伤骨髓基质细胞的细胞周期比例、DNA含量和形态的改变可能是导致放射复合伤造血微环境损伤的重要原因之一。

CONCLUSION : The change of cell morphology and capacity of CFU - F for bone marrow stromal cells is one of impairment injury mechanism of bone marrow hematopoietic inductive microenvironment from PBSCT patients post pretreatment .

结论：外周血干细胞移植患者预处理后骨髓基质细胞不同程度损伤，放化组基质细胞的损伤重于单化组，是导致造血功能恢复缓慢的原因。

Conclusion Bone marrow CFU-F are pluripotential stromal stem cells which are capable of proliferating and differentiating into all stromal cells lines necessary for the formation of bone and reconstitution of the hematopoietic inductive microenvironment .

结论：骨髓基质CFU－F为基质多能干细胞，能增生分化为成骨以及造血诱导微环境所必需的各种基质细胞系。